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TOKSISITAS AKUT EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA (L) R.M. KING & H. ROB) PADA MENCIT PUTIH JANTAN

Medical and Health Science Journal

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Title TOKSISITAS AKUT EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA (L) R.M. KING & H. ROB) PADA MENCIT PUTIH JANTAN
 
Creator ., Nirwanto
Ariadi, Aried
Arifin, Helmi
 
Subject LD50, delayed toxicity, chromolaena odorata (L) R.M. King & H. Rob Te
 
Description Abstract: The acute toxicity of ethanol extracts from Kirinyuh (Chromolaena odorata (L) R.M.King & H. Rob) leaves to white mice males has been done. Parameters toxicity observed were LD50and delayed toxic effects for 14 days of observation including changes in weight, volume of waterconsumption, and relative weight of the organs like heart, liver, kidneys, stomach and lungs. Theethanol extract of Chromolaena odorata (L) R.M King & H. Rob leaves orally at a dose of 4 g/kgBB,8 g/kgBB and 16 g/kgBB, showed that was categorized practically non-toxic (LD50> 15 g/kgBB).Delayed toxic effects are seen from the significant differences in body weight, the volume of water,relative organ weight of lung and stomach (P<0.05). There were no significant differences in therelative organ weight of the heart, liver and kidneys (P<0.05).
 
Publisher UNUSA Press
 
Date 2018-04-28
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://journal2.unusa.ac.id/index.php/MHSJ/article/view/602
10.33086/mhsj.v1i2.602
 
Source Medical and Health Science Journal; Vol. 1 No. 2 (2017): AUGUST
Jurnal Ilmu Kesehatan dan Kesehatan; Vol 1 No 2 (2017): AUGUST
2549-7596
2549-7588
10.33086/mhsj.v1i2
 
Language eng
 
Relation https://journal2.unusa.ac.id/index.php/MHSJ/article/view/602/532