Record Details

Effect Of Roselle Petal Extract On Decreased Levels Of Mda In Rats With Type 2 Diabetes

Journal of Health Sciences

View Archive Info
 
 
Field Value
 
Title Effect Of Roselle Petal Extract On Decreased Levels Of Mda In Rats With Type 2 Diabetes
 
Creator Herdiani, Novera
Wikurendra, Edza Aria
 
Subject Diabetes Mellitus
MDA
Rosella
 
Description Introduction: Diabetes mellitus type 2 is a metabolic disorder, namely a decrease in peripheral tissues' response to insulin. Free radicals increase, which results in the forming of Malondialdehyde (MDA). Roselle flower petals is an antioxidant to reduce free radical damage. Purpose: This study aims to analyze the effect of roselle petal extract on decreased MDA levels in mice induced by diabetes. Method: The rats were divided into four treatments group as follow: 1) control negative, 2) control positive, 3) treatment dose I (administering roselle petal extract 195 mg/200 gram body weight), 4) treatment dose II (giving roselle petal extract 260mg/ 200 gram body weight). MDA levels were measured using Thiobarbituric acid (TBA) assay. Result: There was an effect of rosella petal extract in the group with 260 mg/200 of rosella petal extract (p=0.005) and 195 mg/200 of rosella petal extract (p=0.041) compared with the positive control group. Conclusion: rosella petal extract significantly reduces MDA levels in rats induced by type 2 diabetes.
 
Publisher Universitas Nahdlatul Ulama Surabaya
 
Date 2021-02-26
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://journal2.unusa.ac.id/index.php/JHS/article/view/1688
10.33086/jhs.v14i1.1688
 
Source Journal of Health Sciences; Vol. 14 No. 1 (2021): Jurnal Ilmu Kesehatan (Journal of Health Sciences); 48-52
Jurnal Ilmiah Kesehatan; Vol 14 No 1 (2021): Jurnal Ilmu Kesehatan (Journal of Health Sciences); 48-52
2477-3948
1978-6743
10.33086/jhs.v14i1
 
Language eng
 
Relation https://journal2.unusa.ac.id/index.php/JHS/article/view/1688/1284
 
Rights Copyright (c) 1970 Novera Herdiani
https://creativecommons.org/licenses/by-sa/4.0