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BLOOD LEAD CONCENTRATIONS AND THE NEUROPSYCHOLOGY SCORES OF PREGNANT WOMEN IN KLANG VALLEY, MALAYSIA

Indonesian Journal of Medical Laboratory Science and Technology

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Title BLOOD LEAD CONCENTRATIONS AND THE NEUROPSYCHOLOGY SCORES OF PREGNANT WOMEN IN KLANG VALLEY, MALAYSIA
 
Creator Shamsudin, Shamsul Bahari
Hashim, Jamal Hisham
Ismail, Nik Nasri Nik
Koentjoro, Maharani Pertiwi
 
Subject Neuropsychological scores
blood lead concentrations
pregnant mothers
 
Description Pregnant women with high blood lead posed high risk to their fetus as placental transfer can occurs to the fetus. The objective of this study was to identify the relationship between blood lead and the neuropsychological score of women who were in their 3rd trimester of pregnancy. These respondents were undergoing a routine antenatal checkup at a teaching hospital located in Klang Valley areas.  Blood lead concentrations were analyzed using graphite furnace Atomic Absorption Spectrophotometer (AAS). The neuropsychological scores were measured with WHO Neurobehavioral Core Test battery (NCTB). The test consists of 7 items, which made up of the Digit Symbol, Trail Making, Digit Span, Benton Visual Retention Test, Pursuit Aiming, Santa Ana Manual Dexterity, Reaction Time and Movement Time tests. The mean blood lead was 7.78±4.77 µg/dL. The mean score for the total NCTB test was 50.00±5.24. Statistical analysis showed blood lead concentrations were inversely correlated with the total NCTB score (r= –0.462, p≤0.01). The correlation was about 21.3%. The General Linear Model (GLM) showed that age (β= –0.15, p=0.017), weight (β=2.67, p=0.05) and height (β=–1.97, p=0.05) also influence the total neuropsychological scores. In conclusion, blood lead reduces the total neuropsychological scores. The scores for each of the 7 items were inversely and significantly correlated with blood lead concentrations except for the Trail Making and Santa Ana Manual Dexterity tests.
 
Publisher UNUSA PRESS
 
Date 2020-04-09
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://journal2.unusa.ac.id/index.php/IJMLST/article/view/1499
10.33086/ijmlst.v2i1.1499
 
Source Indonesian Journal of Medical Laboratory Science and Technology; Vol. 2 No. 1 (2020): Laboratory Examinations Support in Medical Toxicology; 11-20
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI; Vol 2 No 1 (2020): Laboratory Examinations Support in Medical Toxicology; 11-20
2656-9825
2684-6748
10.33086/ijmlst.v2i1
 
Language eng
 
Relation https://journal2.unusa.ac.id/index.php/IJMLST/article/view/1499/1050
 
Rights Copyright (c) 2020 Shamsul Bahari Shamsudin, Jamal Hisham Hashim, Nik Nasri Nik Ismail, Maharani Pertiwi Koentjoro