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Efek Ekstrak Etanol Rimpang Kunyit terhadap Paralisis dan Kematian Cacing Dewasa Ascaris Suum Goeze Secara In Vitro

Jurnal Kedokteran Komunitas

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Title Efek Ekstrak Etanol Rimpang Kunyit terhadap Paralisis dan Kematian Cacing Dewasa Ascaris Suum Goeze Secara In Vitro
 
Creator Khoirunnisa, Sanyuki
Falyani, Silvy Amalia
Damayanti, Dini Sri
 
Description Background: Ascariasis is one of the important health problem in Indonesia. Turmeric rhizome has potential anthelmintic substance. This in vitro study aimed to identify whether turmeric rhizome ethanolic extract caused paralysis and death on Ascaris suum Goeze.Method: This study was an in vitro experimental research used Ascaris suum Goeze in beaker glasses divided into five group concentration of turmeric rhizome ethanolic extract: 0.5%, 1%, 2%, 4%, and 8%. The control groups were given NaCl 0,9% and pyrantel pamoat 5 mg/ml, respectively. The percentage of paralysis and death of A. suum goeze was observed at 1st,2nd,3rd,4th,5th,6th,7th,8th,9th, and 24th hours of observations. Data were analyzed using linear regression using Excel program.Results: The increased concentration of turmeric rhizome ethanolic extract was linear with the increase of its anthelmintic activity. The PC50 value of turmeric rhizome ethanolic extract was 2,05%. The LC50 value of turmeric rhizome ethanolic extract was 3,96%.Conclusion: The turmeric rhizome ethanolic extract has a lower potential compared to pyrantel pamoat as an anthelmintic.Keywords: turmeric rhizome, mortality, Ascaris suum Goeze
 
Publisher Jurnal Kedokteran Komunitas
Jurnal Kedokteran Komunitas
 
Contributor —
 
Date 2020-08-11
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://riset.unisma.ac.id/index.php/jkkfk/article/view/7999
 
Source Jurnal Kedokteran Komunitas; Vol 8, No 2 (2020)
Jurnal Kedokteran Komunitas; Vol 8, No 2 (2020)
 
Language eng
 
Relation http://riset.unisma.ac.id/index.php/jkkfk/article/view/7999/6542
 
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