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PENGARUH PENINGKATAN LAJU ENDAP DARAH TERHADAP HASIL PEMERIKSAAN FERITIN SERUM PADA IBU HAMIL

Medical Technology and Public Health Journal

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Title PENGARUH PENINGKATAN LAJU ENDAP DARAH TERHADAP HASIL PEMERIKSAAN FERITIN SERUM PADA IBU HAMIL
 
Creator nugraha, gilang
Masruroh, Nur
 
Subject Erythrocyte Sedimentation Rate
Feritin
Pregnant Women
Laju Endap Darah
Feritin
Wanita Hamil
 
Description Serum ferritin (SF) examination is a test parameter used to assess iron deposits in the body. SF examination has limitations, the degree is influenced by inflammation because ferritin is an acute phase protein. Elevated SF levels follow the increase in other acute phase proteins, the acute phase proteins of the gamma-globulin group to increase Erythrocyte Sedimentation Rate (ESR), as the proteins neutralize the membrane of the negatively charged erythrocytes Thus accelerating the ESR. Enhanced ESR can also be found in pregnant women, the increase in such ESR occurs during pregnancy. This research aims to determine whether there is an increase in ESR relation to SF examination results in pregnant women. The study used Cross sectional studies conducted in Puskesmas Jagir, Wonokromo, Surabaya City which was conducted in May 2019, with the samples of pregnant women research. Blood sampling is 6 mL and is accommodated as much as 3mL on purple tubes for ESR inspection and 3mL on red tubes for SF examination. Laboratory test results are conducted in correlation tests. A total of 30 pregnant women respondents participated in the study, an average age of 27 years and an average gestational age of 34 weeks. ESR inspection results are 56 mm/hr (range: 27 – 117 mm/hr) and SF 20 ng/mL test result (range: 2 – 149 ng/mL). The correlation test result indicates that there is no increase in the ESR value of the SF level (P = 0.240). It was concluded that the increase in ESR in pregnant women did not affect the results of SF examinations, increased due to hemodilution due to the physiological factor of pregnancy, resulting in decreased blood viscosity and increased blood erythrocyte sedimentation rate.
Pemeriksaan feritin serum (serum feritin, SF) adalah parameter pemeriksaan yang digunakan untuk menilai simpanan zat besi dalam tubuh. Pemeriksaan SF memiliki keterbatasan, kadarnya dipengaruhi oleh adanya peradangan karena feritin merupakan protein fase akut. Peningkatan kadar SF di ikuti dengan peningkatan protein fase akut lainnya, protein fase akut dari golongan gamma-globulin mampu meningkatkan Laju Endap Darah (LED), karena protein golongan tersebut menetralkan membran eritrosit yang bermuatan negatif sehingga mempercepat LED. Peningkatan LED juga dapat ditemukan pada wanita hamil, peningkatan LED tersebut terjadi selama kehamilan. Penelitian ini bertujuan menentukan ada tidaknya hubungan peningkatan LED terhadap hasil pemeriksaan SF pada wanita hamil. Penelitian menggunakan studi Cross sectional yang dilakukan di Puskesmas Jagir, Wonokromo, Kota Surabaya yang dilakukan pada bulan Mei 2019, dengan sampel penelitian wanita hamil. Dilakukan pengambilan darah sebanyak 6 mL dan ditampung sebanyak 3mL pada tabung ungu untuk pemeriksaan LED dan 3mL pada tabung merah untuk pemeriksaan SF. Hasil pemeriksaan laboratorium dilakukan uji korelasi. Sebanyak 30 responden wanita hamil berpartisipasi dalam penelitian ini, umur rata-rata 27 tahun dan usia kehamilan rata-rata 34 minggu. Hasil pemeriksaan LED 56 mm/jam (rentang : 27 – 117 mm/jam) dan hasil pemeriksaan SF 20 ng/mL (rentang : 2 – 149 ng/mL). Hasil uji korelasi menunjukkan bahwa tidak ada hubungan peningkatan nilai LED terhadap kadar SF (P = 0,240). Disimpulkan bahwa peningkatan LED pada wanita hamil tidak mempengaruhi hasil pemeriksaan SF, peningkatan terjadi karena hemodilusi akibat faktor fisiologis kehamilan sehingga mengakibatkan viskositas darah menurun dan meningkatkan laju endap darah.
 
Publisher UNUSA Press
 
Date 2019-09-25
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/1133
10.33086/mtphj.v3i2.1133
 
Source Medical Technology and Public Health Journal; Vol. 3 No. 2 (2019): Medical Technology and Public Health Journal September 2019; 127-132
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM; Vol 3 No 2 (2019): Medical Technology and Public Health Journal September 2019; 127-132
2549-2993
2549-189X
10.33086/mtphj.v3i2
 
Language eng
 
Relation https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/1133/918
 
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