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Uji Potensi Antioksidan Kumis Kucing (Orthosiphon aristatus) dengan Pendekatan In Vitro dan In Silico

Jurnal Kesehatan Islam : Islamic Health Journal

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Title Uji Potensi Antioksidan Kumis Kucing (Orthosiphon aristatus) dengan Pendekatan In Vitro dan In Silico
 
Creator Novita W, Dian
Amalia Falyani, Silvy
 
Subject Orthosiphon aristatus; eupatorine; rosmarinic acid; sinensetin; in vitro; in silico
 
Description Abstract: Orthosiphon aristatus is a potential herb as a source of antioxidants. It is known from previous research, that the active compounds O.aristatus include eupatorin, rosmarinic acid and sinensetin. The study of the potential approach of active compounds extracts O.aristatus with the in vitro methods DPPH (1,1-Difenil-2-Pikrilhidrazil) and in silico using the help of pyrex autodock vina software, with the help of visualization using biovia discovery studio and pymol. Results obtained from in vitro tests using DPPH showed the presence of antioxidant activity with yellow spotting markers against a purple background. Studies in silico show that O.aristatus extract is potentially an antioxidant compound, this is demonstrated through the presence of ligand bonds with glutathione peroksidase (GPX) receptors namely van der Waals bonds, hydrogen bonds and several other bonds.
 
Publisher Publikasi oleh Fakultas Kedokteran Universitas Islam Malang
 
Contributor —
 
Date 2021-11-10
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://riset.unisma.ac.id/index.php/jki/article/view/13823
10.33474/jki.v10i2.13823
 
Source Jurnal Kesehatan Islam : Islamic Health Journal; Vol 10, No 2 (2021): Jurnal Kesehatan Islam : Islamic Health Journal; 53-56
26158345
2303002X
10.33474/jki.v10i2
 
Language eng
 
Relation http://riset.unisma.ac.id/index.php/jki/article/view/13823/pdf
 
Rights Copyright (c) 2021 Dian Novita W, Silvy Amalia Falyani
http://creativecommons.org/licenses/by-sa/4.0